Idiopathic generalised epilepsies of adolescence

Idiopathic generalised epilepsies are frequent and onset is in infancy to adolescence. Idiopathic generalised epilepsies are genetically determined (see section on genetic and molecular basis). Neuroimaging is normal and suggestions that morphological cortical abnormalities might underlie idiopathic generalised epilepsies have not been confirmed. As the result of the overlapping features between different idiopathic generalised epilepsies, the term idiopathic generalised epilepsies with variable phenotypes has been suggested as all-inclusive. Social adjustment is usually good but some patients have behavioural or learning difficulties.
Seizures are primarily generalised absence, myoclonic, and tonic-clonic. Interictal EEG abnormalities are 3 Hz generalised spike/polyspike and wave discharges.
Most patients respond to antiepileptic drugs but response is drug-specific.

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